HCID 59379937, 화합물 → HCID 59379931, 화합물

HRID 2353723노트

반응식

[F:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH2:11][C:12]2[CH:17]=[C:16]([N:18]3[CH2:23][CH2:22][O:21][CH2:20][C@@H:19]3[CH3:24])[N:15]=[C:14]([C:25]3[CH:30]=[CH:29][C:28]([NH:31][C:32](=O)[O:33]C4C=CC=CC=4)=[CH:27][CH:26]=3)[N:13]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.FC1C=CC(S(C(C2C=C(N3CCOC[C@@H]3C)N=C([C:67]3[CH:72]=[CH:71][C:70]([NH:73]C(=O)OC4C=CC=CC=4)=CC=3)N=2)(C)C)(=O)=O)=CC=1>>[CH:70]1([NH:73][C:32](=[O:33])[NH:31][C:28]2[CH:27]=[CH:26][C:25]([C:14]3[N:13]=[C:12]([CH2:11][S:8]([C:5]4[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=4)(=[O:10])=[O:9])[CH:17]=[C:16]([N:18]4[CH2:23][CH2:22][O:21][CH2:20][C@@H:19]4[CH3:24])[N:15]=3)=[CH:30][CH:29]=2)[CH2:71][CH2:72][CH2:67]1

참가 물질

반응물 2

HCID 59379937HCID 59379937, 화합물

HCID 59379980HCID 59379980, 화합물

생성물 1

HCID 59379931HCID 59379931, 화합물

실험 절차

The following compounds were made in an analogous fashion from phenyl N-[4-[4-[(4-fluorophenyl)sulfonylmethyl]-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]carbamate or phenyl N-[4-[4-[2-(4-fluorophenyl)sulfonylpropan-2-yl]-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]carbamate and the appropriate amine.

출처 및 근거

ORD 기록: ord-af129f3dbaab461e8a58a60bf227a867
출처 데이터셋: uspto-grants-2010_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07750003B2

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