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HRID 235527생성일: 2026년 10월 26일

Tryptamine hydrochloride → (S)-N-Benzyl-N-methyl-2-[[2-(1H-indol-3-yl)-ethylamino]-N'-(t-butoxycarbonyl)-ethylamino]-3-phenyl-propionamide

https://huagongshe.com/reaction/235527

반응식

참여 물질

역할이름HCID투입량
반응물Tryptamine hydrochlorideHCID 67652—
반응물(S)-N-benzyl-N-methyl-2-[N-(t-butoxycarbonyl)-2-oxo-ethylamino]-3-phenyl-propionamideHCID 53842533—
생성물(S)-N-Benzyl-N-methyl-2-[[2-(1H-indol-3-yl)-ethylamino]-N'-(t-butoxycarbonyl)-ethylamino]-3-phenyl-propionamideHCID 86750252—

반응 단계

Prepare by the method of Example 1 using 2-(1H-indol-3-yl)-ethylamine hydrochloride salt (tryptamine hydrochloride salt) (0.197 g, 1.0 mmol) and (S)-N-benzyl-N-methyl-2-[N-(t-butoxycarbonyl)-2-oxo-ethylamino]-3-phenyl-propionamide (0.41 g, 1.0 mmol) to give the title compound: TLC Rf =0.69 (silica gel, 85% chloroform/10% methanol/5% acetic acid).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05597845
출처 데이터셋uspto-grants-1997_01
ORD IDord-0003ab746bf54a9f8ba8d633e3decd4c
출처 메모uspto-grants-1997_01