Pentane → HCID 178506689, 화합물
반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:13]=[CH:14][CH:15]=1)[O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1Br.[Li:16]C(C)(C)C.CCCCC>C1COCC1>[F:1][C:2]1[CH:3]=[C:4]([CH:13]=[CH:14][CH:15]=1)[O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[Li:16]참가 물질
5
반응 조건
- 온도
- -70 °C
실험 절차
To a stirred solution of 1-(3-fluorophenoxy)-2-bromobenzene (1.27 g, 4.75 mmol) in THF (10 mL) at −70° C. was added 1.7 M t-BuLi in pentane (5.6 mL, 9.50 mmol) dropwise to keep the temperature below −70° C. The resulting solution was stirred at −70° C. for 30 min, and used for the next step directly.
후처리
- customthe temperature below −70° C
출처 및 근거
- ORD 기록
- ord-1df3df6ca70f4bd7861dc075e09aec17
- 출처 데이터셋
- uspto-grants-2010_07
- 특허 번호
- US07754737B2
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