참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acrylic Acid | HCID 6581 | — |
| 반응물 | 4-Bromoanisole | HCID 7730 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 촉매 | Palladium Chloride | HCID 24290 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Methoxy cinnamic acid | HCID 13245 | 81.2% |
반응 단계
p-bromo anisole (8.4 g), acrylic acid (3.9 g), water (13.5 g), PdCl2 (0.3 mg) and triethyamine (14.3 g, 89.3% pure by titration, the balance being water, recovered by phase separation from a previous run) were charged into an autoclave and heated for 2 hours at 130° C. The work up detailed in Example 1 gave 6.5 g (81%) of >98% pure p-methoxy cinnamic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05728865 |
|---|
| 출처 데이터셋 | uspto-grants-1998_03 |
|---|
| ORD ID | ord-623e76f5d131438c908eae7b5ce8e7ac |
|---|
| 출처 메모 | uspto-grants-1998_03 |
|---|
