Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acrylamide → 3-(Piperidin-1-yl)propanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acrylamide | HCID 6579 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Propyl ether | HCID 8114 | — |
| 생성물 | 3-(Piperidin-1-yl)propanamide | HCID 566784 | 75% |
반응 단계
A solution of piperidine, 4-(diphenylmethylene) (0.10 mole) and acrylamide (8.95 g, 0.062 mole) in EtOH (50 ml) was refluxed overnight. This reaction mixture was filtered and concentrated. The resulting while solid residue was dissolved in CHCl3, washed with H2O (3×150 ml), dried (Na2SO4) and the solvent removed to give thick yellow oil. Crystallization from CH2Cl2 --i--Pr2O afforded 29.01 g (75%) of 1-piperidinepropanamide, 4-(diphenylmethylene)-; mp 105°-7° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04640925 |
| 출처 데이터셋 | uspto-grants-1987_02 |
| ORD ID | ord-41cfecc7b47843609ffcb8f699a8479d |
| 출처 메모 | uspto-grants-1987_02 |