Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoic Acid → 3-Nitro-5-sulfobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoic Acid | HCID 243 | — |
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Benzoic acid, 3-sulfo- | HCID 8477 | — |
| 반응물 | Sulfur trioxide | HCID 24682 | — |
| 생성물 | 3-Nitro-5-sulfobenzoic acid | HCID 2749185 | — |
반응 단계
Benzoic acid was sulfonated by heating it with concentrated sulfuric acid in the presence of sulfur trioxide. The 3-sulfobenzoic acid was nitrated with fuming nitric acid to yield 3-nitro-5-sulfobenzoic acid. Hydrogenation of this in 50% ethanol/water over palladium on charcoal easily afforded 3-amino-5-sulfobenzoic acid in good yield. Structural verification was obtained by carbon magnetic resonance, proton magnetic resonance and infra-red analysis.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04642240 |
| 출처 데이터셋 | uspto-grants-1987_02 |
| ORD ID | ord-747374bb87c74b8c8c7bfdc4ca2aba2a |
| 출처 메모 | uspto-grants-1987_02 |