Water → HCID 59304580, 화합물

HRID 2357877노트

반응식

HRID 2357877 반응식
[CH2:1]([C:3]1[C:12]2[C:11](=[O:13])[NH:10][C:9](=[S:14])[NH:8][C:7]=2[O:6][C:5](=[O:15])[CH:4]=1)[CH3:2].O.[CH3:17]N(C=O)C>>[CH2:1]([C:3]1[C:12]2[C:11](=[O:13])[NH:10][C:9]([S:14][CH3:17])=[N:8][C:7]=2[O:6][C:5](=[O:15])[CH:4]=1)[CH3:2]

참가 물질

4

반응물 3

HCID 962WaterHCID 6228DimethylformamideHCID 533226895-ethyl-2-mercapto-3H-pyrano[2,3-d]pyrimidine-4,7-dione

생성물 1

HCID 59304580HCID 59304580, 화합물수율 96%

실험 절차

Mel (2.23 mL, 35.72 mmol) was added to a suspension of 5-ethyl-2-thioxo-2,3-dihydro-1h-pyrano[2,3-d]pyrimidine-4,7-dione (4.0 g, 17.86 mmol) in DMF (40 mL) at room temperature. The reaction mixture was stirred at room temperature overnight. The reaction mixture was then poured into water (250 mL) and filtered through a sintered funnel. The solid residue was washed with water (2×50 mL) and dried under vacuum to give 5-ethyl-2-methylsulfanyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione (4.1 g, 96%).

후처리

  1. filtrationfiltered through a sintered funnel
  2. washThe solid residue was washed with water (2×50 mL)
  3. customdried under vacuum

출처 및 근거

ORD 기록
ord-97fd655668d64ad5ae02c0b86fa9b5ab
출처 데이터셋
uspto-grants-2010_07
특허 번호
US07763623B2

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