Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 2-Hydroxy-4-methoxybenzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 4-Methoxysalicylic Acid | HCID 75231 | — |
| 용매 | 1,2-Dichloroethane | HCID 11 | — |
| 생성물 | 2-Hydroxy-4-methoxybenzoyl chloride | HCID 23118559 | 99.1% |
반응 단계
To a solution of 2-hydroxy-p-anisic acid (0.2 g, 1.2 mmol) in DCE (8 mL) was added thionyl chloride (0.13 mL, 1.8 mmol) and a drop of DMF. After stirring at room temperature for 4.5 h the reaction mixture was concentrated and azeotroped several times with benzene to give the acid chloride 123 as a white solid (222 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07763614B2 |
| 출처 데이터셋 | uspto-grants-2010_07 |
| ORD ID | ord-bfaddc38c3fc471697e8ad06e946ba5b |
| 출처 메모 | uspto-grants-2010_07 |