3-(4-tert-Butylphenyl)-2-methylprop-2-enoic acid → 3-(4-tert-Butylphenyl)-2-methylpropanoic acid
반응식
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[C:12]([CH3:16])[C:13]([OH:15])=[O:14])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]>[Pd].CO>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH:12]([CH3:16])[C:13]([OH:15])=[O:14])=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]참가 물질
4
실험 절차
3-(4-tert-butylphenyl)-2-methylacrylic acid (40.9 mg, 0.19 mmol) and 10 wt. % palladium on activated carbon were added in methanol. The reaction mixture was stirred for 5 hrs under H2 gas. The reaction mixture was filtered with Celite. The filterate was concentrated in vacuo to obtain title compound (39.1 mg, 93.47%).
후처리
- filtrationThe reaction mixture was filtered with Celite
- concentrationThe filterate was concentrated in vacuo
출처 및 근거
- ORD 기록
- ord-8ef4a8f9a6be45418e08ae4eb8b5e5a0
- 출처 데이터셋
- uspto-grants-2010_07
- 특허 번호
- US07763657B2
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