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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Potassium Carbonate → 3-(4-Methyl-2-nitro-phenylsulfanyl)-phenylamine

HRID 2358631
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HRID 2358631 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5](OS(C(F)(F)F)(=O)=O)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1.[NH2:19][C:20]1[CH:21]=[C:22]([SH:26])[CH:23]=[CH:24][CH:25]=1.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C.O>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:26][C:22]2[CH:21]=[C:20]([NH2:19])[CH:25]=[CH:24][CH:23]=2)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1
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참가 물질

6

반응물 3

HCID 11430Potassium CarbonateHCID 315773-AminothiophenolHCID 713468894-Methyl-2-nitrophenyl trifluoromethanesulfonate

생성물 1

HCID 684579173-(4-Methyl-2-nitro-phenylsulfanyl)-phenylamine

시약·촉매·용매 2

HCID 962Water용매HCID 6228Dimethylformamide용매

반응 조건

온도
10 °C

실험 절차

The product from Example 4a (1.00 g, 3.51 mmol) and 3-Amino-benzenethiol (658 mg, 5.26 mmol) were dissolved in DMF to which was added K2CO3 (848 mg, 6.14 mmol). The reaction mixture was then heated to 10° C. for 16 hrs. Reaction mixture was then cooled to room temperature, diluted with water and extracted with ethyl acetate providing the title compound (650 mg, 71%).

후처리

  1. customReaction mixture
  2. temperaturewas then cooled to room temperature
  3. extractionextracted with ethyl acetate providing the title compound (650 mg, 71%)

출처 및 근거

ORD 기록
ord-32c5efcd8b4a43468ae3225ab42929ce
출처 데이터셋
uspto-grants-2010_07
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07763731B2

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