Ammonium Hydroxide → 3-(4-Chloro-2-nitro-phenoxy)-benzamide
반응식
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=2)[C:10](Cl)=[O:11])=[C:4]([N+:18]([O-:20])=[O:19])[CH:3]=1.[NH4+:21].[OH-]>O>[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=2)[C:10]([NH2:21])=[O:11])=[C:4]([N+:18]([O-:20])=[O:19])[CH:3]=1참가 물질
4
실험 절차
The product from Example 168b (1.8 g, 6.13 mmol) was added to cold NH4OH (15 mL) and stirred for 1 h. The reaction was poured into water and extracted with ethyl acetate. The organic layer washed with water, brine, and dried over sodium sulfate, filtered and concentrated under vacuum to gave the title compound (1.66 g, 92%).
후처리
- extractionextracted with ethyl acetate
- washThe organic layer washed with water, brine
- dry with materialdried over sodium sulfate
- filtrationfiltered
- concentrationconcentrated under vacuum
출처 및 근거
- ORD 기록
- ord-600ca7701d494de6b6a2fc8f50f870ec
- 출처 데이터셋
- uspto-grants-2010_07
- 특허 번호
- US07763731B2
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