8-Quinolinol, 5-(chloromethyl)-, hydrochloride (1:1) → Hla-20

HRID 2358941노트

반응식

HRID 2358941 반응식
Cl.Cl[CH2:3][C:4]1[CH:13]=[CH:12][C:11]([OH:14])=[C:10]2[C:5]=1[CH:6]=[CH:7][CH:8]=[N:9]2.[CH2:15]([N:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1)[C:16]#[CH:17]>>[CH2:15]([N:18]1[CH2:23][CH2:22][N:21]([CH2:3][C:4]2[CH:13]=[CH:12][C:11]([OH:14])=[C:10]3[C:5]=2[CH:6]=[CH:7][CH:8]=[N:9]3)[CH2:20][CH2:19]1)[C:16]#[CH:17]

참가 물질

3

반응물 2

HCID 122695968-Quinolinol, 5-(chloromethyl)-, hydrochloride (1:1)HCID 146273691-(2-Propynyl)piperazine

생성물 1

HCID 6918819Hla-20

실험 절차

The title compound was prepared by reaction of 5-chloromethyl-8-hydroxyquinolinoline (A2) with N-propargyl piperazine as follows:

출처 및 근거

ORD 기록
ord-03866808fd904a1ca9179c06a7e440cf
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08685955B2

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