1-Isocyanato-4-methoxybenzene → 1-Benzylindolin-5-yl 4-methoxyphenylcarbamate

HRID 2360123노트

반응식

HRID 2360123 반응식
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([N:26]=[C:27]=[O:28])=[CH:22][CH:21]=1>>[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([NH:26][C:27](=[O:28])[O:17][C:13]2[CH:12]=[C:11]3[C:16](=[CH:15][CH:14]=2)[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:9][CH2:10]3)=[CH:22][CH:21]=1

참가 물질

3

반응물 2

HCID 794431-Isocyanato-4-methoxybenzeneHCID 866598571-Benzylindolin-5-ol

생성물 1

HCID 468660481-Benzylindolin-5-yl 4-methoxyphenylcarbamate

실험 절차

The title compound was synthesized from 1-benzylindolin-5-ol (30.0 mg, 0.133 mmol) using the same procedure employed for Example 2 (2), but with 4-methoxyphenylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a white solid (13.2 mg, 27%) having the following characteristics.

출처 및 근거

ORD 기록
ord-e34fd93a4adf4385b2af2e957ce5806e
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08686024B2

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