4-Bromoaniline → 2′-Chloro[1,1′-biphenyl]-4-amine

HRID 2360461노트

반응식

HRID 2360461 반응식
Br[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1B(O)O>>[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 78074-BromoanilineHCID 27343222-Chlorophenylboronic acid

생성물 1

HCID 41273512′-Chloro[1,1′-biphenyl]-4-amine수율 49.7%

실험 절차

The title compound (176 mg) was prepared from 4-bromoaniline (300 mg, 1.74 mmol) and 2-chlorophenylboronic acid (354 mg, 2.26 mmol) as a yellow solid.

출처 및 근거

ORD 기록
ord-78a42e7ed24f4987af59a7be6fe8d315
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08686048B2

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