참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | Ameltolide | HCID 13086 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-(acetylamino)-N-(2,6-dimethylphenyl)benzamide | HCID 443227 | 85% |
반응 단계
To a solution of 2.0 g of 4-amino-N-(2,6-dimethylphenyl)benzamide in dimethylformamide were added 1 ml of pyridine followed by 710 μl of acetyl chloride. The reaction was stirrred at room temperature for 2 hours, diluted with water, and chilled to approximately 4° C. The title product was recovered by filtration in 85% yield, m.p. 293°-295° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04642379 |
|---|
| 출처 데이터셋 | uspto-grants-1987_02 |
|---|
| ORD ID | ord-0da184272f6b474bb5fac4687f8f7171 |
|---|
| 출처 메모 | uspto-grants-1987_02 |
|---|
