Ammonia → 8-Hydroxy-2-methyl-7-quinolinecarboxamide

HRID 236131

반응식

HRID 236131 반응식
C[O:2][C:3]([C:5]1[C:14]([OH:15])=[C:13]2[C:8]([CH:9]=[CH:10][C:11]([CH3:16])=[N:12]2)=[CH:7][CH:6]=1)=O.[NH3:17]>>[OH:15][C:14]1[C:5]([C:3]([NH2:17])=[O:2])=[CH:6][CH:7]=[C:8]2[C:13]=1[N:12]=[C:11]([CH3:16])[CH:10]=[CH:9]2

참가 물질

3

반응물 2

HCID 222Ammonia2회HCID 545112118-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester

생성물 1

HCID 212714728-Hydroxy-2-methyl-7-quinolinecarboxamide

실험 절차

8-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester is reacted with excess ammonia in a steel bomb for 12-18 hr. The excess ammonia is allowed to evaporate and the residue is crystallized from a suitable solvent to give the title compound.

후처리

  1. customto evaporate
  2. customthe residue is crystallized from a suitable solvent

출처 및 근거

ORD 기록
ord-833cdc1c912c44cfbecbe45644db9f04
출처 데이터셋
uspto-grants-1987_02
특허 번호
US04642343

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