Methyl Methanesulfonate → 3-Amino-2-methyl-5,6-bis(4-methylphenyl)-1,2,4-triazine mesylate

HRID 2361860노트

반응식

HRID 2361860 반응식
[NH2:1][C:2]1[N:3]=[N:4][C:5]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[N:7]=1.[CH3:22][S:23]([O:26]C)(=[O:25])=[O:24]>CO>[S:23]([OH:26])(=[O:25])(=[O:24])[CH3:22].[NH2:1][C:2]1[N:3]([CH3:22])[NH:4][C:5]([C:15]2[CH:16]=[CH:17][C:18]([CH3:21])=[CH:19][CH:20]=2)=[C:6]([C:8]2[CH:9]=[CH:10][C:11]([CH3:14])=[CH:12][CH:13]=2)[N:7]=1

참가 물질

4

반응물 2

HCID 4156Methyl MethanesulfonateHCID 581031023-Amino-5,6-bis(4-methylphenyl)-1,2,4-triazine

생성물 1

HCID 866497323-Amino-2-methyl-5,6-bis(4-methylphenyl)-1,2,4-triazine mesylate

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of 3-amino-5,6-bis(4-methylphenyl)-1,2,4-triazine (500 mg), methyl methanesulphonate (0.5 cm3) and methanol (10 cm3) was stirred at 40° for 24 hours and then evaporated to dryness. The resulting yellow solid was recrystallised from acetone giving the title compound as pale yellow needles,

후처리

  1. customevaporated to dryness
  2. customThe resulting yellow solid was recrystallised from acetone giving the title compound as pale yellow needles

출처 및 근거

ORD 기록
ord-74a29c942b2c4c80a58efd4e91438d1d
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08691818B2

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