Triethylamine → 2-Methoxy-5-methyl-2-oxo-1,3,2-benzodioxaphosphole

HRID 236214

반응식

HRID 236214 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH3:9])[CH:5]=[CH:6][C:7]=1[OH:8].C(N(CC)CC)C.[P:17](Cl)(Cl)([O:19][CH3:20])=[O:18]>CCOCC>[CH3:20][O:19][P:17]1(=[O:18])[O:8][C:7]2[CH:6]=[CH:5][C:4]([CH3:9])=[CH:3][C:2]=2[O:1]1

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 99584-MethylcatecholHCID 69611Methyl dichlorophosphate

생성물 1

HCID 200766172-Methoxy-5-methyl-2-oxo-1,3,2-benzodioxaphosphole수율 88,319%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

3,4-Dihydroxytoluene (1.686 g, 13.58 mM) was dissolved in 40 ml of ether and, using 2.748 g of triethylamine and 2.022 g of methyl dichlorophosphate, the reaction mixture was treated in the same manner as in Reference Example 5. There was obtained 2,400 g (88.4% yield) of 2-methoxy-5-methyl-2-oxo-1,3,2-benzodioxaphosphole as a viscous oil.

후처리

  1. additionthe reaction mixture was treated in the same manner as in Reference Example 5

출처 및 근거

ORD 기록
ord-8ed33eeaef5d46cba414616aef0b1f78
출처 데이터셋
uspto-grants-1987_02
특허 번호
US04642365

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