참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Ethyl 2-bromopropionate | HCID 79040 | — |
| 반응물 | 7-Hydroxyisoflavone | HCID 5376891 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Ethyl 2-[(4-oxo-3-phenyl-4H-chromen-7-yl)oxy]propionate | HCID 3579826 | 181.3% |
반응 단계
A mixture of 40 g of 7-hydroxy-3-phenyl-4H-1-benzopyran-4-one, 46 g of ethyl 2-bromopropionate, 250 ml of dimethylformamide and 46.5 g of potassium carbonate was stirred well with heating at 80° C. for 2 hours and poured into 270 ml of ice water. The resulting crystalline precipitate was collected by filtration and recrystallized from ethyl acetate-ethanol to give 103 g of 7-(1-ethoxycarbonylethyl)oxy-3-phenyl-4H-1-benzopyran-4-one as white crystals. m.p. 165°-166° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04644012 |
|---|
| 출처 데이터셋 | uspto-grants-1987_02 |
|---|
| ORD ID | ord-23d214a5cf28460687112731cb37a5d4 |
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| 출처 메모 | uspto-grants-1987_02 |
|---|
