Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-((4-Oxo-3-phenyl-4H-1-benzopyran-7-yl)oxy)propanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 반응물 | Ethyl 2-[(4-oxo-3-phenyl-4H-chromen-7-yl)oxy]propionate | HCID 3579826 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-((4-Oxo-3-phenyl-4H-1-benzopyran-7-yl)oxy)propanoic acid | HCID 3062797 | 93.2% |
반응 단계
A mixture of 20 g of 7-(1-ethoxycarbonylethyl)oxy-3-phenyl-4H-1-benzopyran-4-one, 200 ml of dioxane, 70 ml of hydrochloric acid and 150 ml of water was refluxed for 4 hours and poured into ice water. The resulting crystalline precipitate was collected by filtration and recrystallized from ethanol to give 17.1 g of 7-(1-hydroxycarbonylethyl)oxy-3-phenyl-4H-1-benzopyran-4-one as white crystals. m.p. 223° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04644012 |
| 출처 데이터셋 | uspto-grants-1987_02 |
| ORD ID | ord-ce9c24a4f6ea45f18a9d5252defdb5da |
| 출처 메모 | uspto-grants-1987_02 |