Ethyl 6-[1-(triisopropylsilyl)-1H-pyrrol-3-yl]imidazo[1,2-a]pyridine-2-carboxylate → HCID 178469438, 화합물

HRID 2363736노트

반응식

HRID 2363736 반응식
C([Si](C(C)C)(C(C)C)[N:5]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13]3[N:14]([CH:16]=[C:17]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[N:18]=3)[CH:15]=2)=C1)(C)C.[NH:30]1C=CC(B(O)O)=N1>>[NH:5]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13]3[N:14]([CH:16]=[C:17]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[N:18]=3)[CH:15]=2)=[N:30]1

참가 물질

3

반응물 2

HCID 44136203Ethyl 6-[1-(triisopropylsilyl)-1H-pyrrol-3-yl]imidazo[1,2-a]pyridine-2-carboxylateHCID 178514837HCID 178514837, 화합물

생성물 1

HCID 178469438HCID 178469438, 화합물

실험 절차

This product is prepared under conditions similar to those described for the preparation of Intermediate 15 (step 15.1), replacing the 1-(triisopropylsilyl)pyrrole-3-boronic acid with pyrazole-3-boronic acid.

후처리

  1. customThis product is prepared under conditions similar to

출처 및 근거

ORD 기록
ord-03aaae13ec54477197bad483352d3dd2
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08691990B2

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