5-Aminovaleric acid → 5-(3-Hexadecanoyloxyoctadecanoyl)aminovaleric acid

HRID 236486

반응식

HRID 236486 반응식
[C:1]([O:18][CH:19]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:20][C:21]([OH:23])=O)(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[NH2:39][CH2:40][CH2:41][CH2:42][CH2:43][C:44]([OH:46])=[O:45]>>[C:1]([O:18][CH:19]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:20][C:21]([NH:39][CH2:40][CH2:41][CH2:42][CH2:43][C:44]([OH:46])=[O:45])=[O:23])(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

참가 물질

3

반응물 2

HCID 1385-Aminovaleric acidHCID 134890283-Hexadecanoyloxyoctadecanoic acid

생성물 1

HCID 133718635-(3-Hexadecanoyloxyoctadecanoyl)aminovaleric acid수율 89.5%

실험 절차

Starting from 3-hexadecanoyloxyoctadecanoic acid (5.38 g) prepared by the method described in Preparation A-2 (5) and 5-aminopentanoic acid (5 g), N-(3-hexadecanoyloxyoctadecanoyl)-5-aminopentanoic acid (5.7 g) was obtained as crystals according to a similar manner to that of Preparation B-1. M.p. 66°-67°.

후처리

  1. customprepared by the method

출처 및 근거

ORD 기록
ord-821f914595b8492386123b2208d94bc7
출처 데이터셋
uspto-grants-1987_02
특허 번호
US04643990

연결된 노트

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