Ethyl Acetate → 7-(3-fluoro-4-(trifluoromethyl)phenyl)-4-(pyrimidin-2-ylmethyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one

반응식

Br[C:2]1[CH:3]=[CH:4][C:5]2[O:11][CH2:10][CH2:9][N:8]([CH2:12][C:13]3[N:18]=[CH:17][CH:16]=[CH:15][N:14]=3)[C:7](=[O:19])[C:6]=2[CH:20]=1.[F:21][C:22]1[CH:23]=[C:24](B2OC(C)(C)C(C)(C)O2)[CH:25]=[CH:26][C:27]=1[C:28]([F:31])([F:30])[F:29].C(=O)([O-])[O-].[Cs+].[Cs+].CCOC(C)=O>CN(C=O)C.O.C1(P(C2C=CC=CC=2)[C-]2C=CC=C2)C=CC=CC=1.[C-]1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=C1.[Fe+2].Cl[Pd]Cl>[F:21][C:22]1[CH:23]=[C:24]([C:2]2[CH:3]=[CH:4][C:5]3[O:11][CH2:10][CH2:9][N:8]([CH2:12][C:13]4[N:18]=[CH:17][CH:16]=[CH:15][N:14]=4)[C:7](=[O:19])[C:6]=3[CH:20]=2)[CH:25]=[CH:26][C:27]=1[C:28]([F:29])([F:30])[F:31]