HCID 57517484, 화합물 → 1344684-60-1

HRID 2368081노트

반응식

HRID 2368081 반응식
[N:1]([CH:4]([CH3:20])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1)=[N+]=[N-]>CO.[Pd]>[NH2:1][CH:4]([CH3:20])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1

참가 물질

4

반응물 1

HCID 57517484HCID 57517484, 화합물

생성물 1

HCID 575174851344684-60-1수율 103.8%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

A suspension of tert-butyl 4-(3-azidobutyl)piperidine-1-carboxylate (3.81 g) and 5% palladium/carbon (containing water (50%), 800 mg) in methanol (100 mL) was stirred at room temperature for 15 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (3.59 g).

후처리

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-a789f81dd182482882a7121e7fcd1e46
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08703758B2

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