Hydrogen chloride-ethyl acetate → HCID 67449164, 화합물

HRID 2368083노트

반응식

HRID 2368083 반응식
[C:1]([NH:4][CH:5]([CH3:21])[CH2:6][CH2:7][CH:8]1[CH2:13][CH2:12][N:11](C(OC(C)(C)C)=O)[CH2:10][CH2:9]1)(=[O:3])[CH3:2].[ClH:22].C(OCC)(=O)C>C(OCC)(=O)C>[ClH:22].[CH3:21][CH:5]([NH:4][C:1](=[O:3])[CH3:2])[CH2:6][CH2:7][CH:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1

참가 물질

4

반응물 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 67447123HCID 67447123, 화합물

생성물 1

HCID 67449164HCID 67449164, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

To a solution of tert-butyl 4-[3-(acetylamino)butyl]piperidine-1-carboxylate (2.65 g) in ethyl acetate (30 mL) was added 4 M hydrogen chloride/ethyl acetate (10 mL), and the mixture was stirred at room temperature for 3 hr. The resulting precipitate was collected by filtration to give the title compound (2.06 g).

후처리

  1. filtrationThe resulting precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-0581df7d97994bf98d75189e57ceff52
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08703758B2

반응 노트

불러오는 중…