(3-Aminopropyl)triethoxysilane → alpha-D-Mannopyranose

HRID 2369766

반응식

HRID 2369766 반응식
C1(NC2C(=O)C(=O)C=2)C=CC=CC=1.[OH:14][C@H:15]1[O:23][C@H:22]([CH2:24][OH:25])[C@@H:20]([OH:21])[C@H:18]([OH:19])[C@@H:16]1[OH:17].NCCC[Si](OCC)(OCC)OCC>C(O)C.O.C(N(CC)CC)C.CCO>[OH:14][C@H:15]1[O:23][C@H:22]([CH2:24][OH:25])[C@@H:20]([OH:21])[C@H:18]([OH:19])[C@@H:16]1[OH:17]

참가 물질

6

반응물 2

HCID 13521(3-Aminopropyl)triethoxysilaneHCID 86678081alpha-Mannose phenylaminocyclobutenedione2회

생성물 1

HCID 185698alpha-D-Mannopyranose

시약·촉매·용매 3

HCID 702Ethanol용매HCID 8471Triethylamine용매HCID 19096565Water ethanol용매

실험 절차

α-mannose phenylaminocyclobutenedione (250 mg; 0.37 mmol) was dissolved in a mixture of Ethanol/H2O (3/2) (10 mL) and triethyamine (400 μL) was added dropwise to the solution of APTS (Aminopropyltriethoxysilane) grafted nanoparticles DB060 (250 mg in 10 ml of EtOH). The mixture was stirred during 16 h. The nanoparticles were then centrifugated and washed with water and ethanol and dried under vacuum to afford 232 mg of grafted nanoparticles. The concentration of α-mannose phenylaminocyclobutenedione grafted on the surface of the DB103 nanoaprticle is 0.089 mmol/g.

후처리

  1. washwashed with water and ethanol
  2. customdried under vacuum
  3. customto afford 232 mg of grafted nanoparticles

출처 및 근거

ORD 기록
ord-b8eeaa78aaa64ca1b8ddeca525e5f66a
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08709747B2

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