Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Hydroxypiperidine → 1-(4-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl)piperidin-3-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Hydroxypiperidine | HCID 23293 | — |
| 반응물 | 2-(4-Bromophenyl)-5-methyl-1,3,4-oxadiazole | HCID 540693 | — |
| 생성물 | 1-(4-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl)piperidin-3-ol | HCID 71227550 | 37% |
반응 단계
1-(4-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl)piperidin-3-ol (120 mg, 0.463 mmol, 37% yield) was synthesized as described in General Procedure B using 2-(4-bromophenyl)-5-methyl-1,3,4-oxadiazole (300 mg, 1.255 mmol) and piperidin-3-ol (254 mg, 2.51 mmol). Anal. Calcd. for C14H17N3O2 m/z 259.3, found: 260.0 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08710049B2 |
| 출처 데이터셋 | uspto-grants-2014_04 |
| ORD ID | ord-d0eebd16ebef4398b768c5348ba97afa |
| 출처 메모 | uspto-grants-2014_04 |