5-(3-Methylbenzyl)-2-thiouracil → 2-[2-(5-Methyl-4-imidazolylmethylthio)ethylamino]-5-(4-methylbenzyl)-4-pyrimidone dihydrochloride
반응식
[ClH:1].Cl.[CH3:3][C:4]1[NH:8][CH:7]=[N:6][C:5]=1[CH2:9][S:10][CH2:11][CH2:12][NH:13][C:14]1[NH:19][C:18](=[O:20])[C:17]([CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[C:24](C)[CH:23]=2)=[CH:16][N:15]=1.[CH3:29]C1C=C(C=CC=1)CC1C(=O)NC(=S)NC=1>>[ClH:1].[ClH:1].[CH3:3][C:4]1[NH:8][CH:7]=[N:6][C:5]=1[CH2:9][S:10][CH2:11][CH2:12][NH:13][C:14]1[NH:19][C:18](=[O:20])[C:17]([CH2:21][C:22]2[CH:23]=[CH:24][C:25]([CH3:29])=[CH:26][CH:27]=2)=[CH:16][N:15]=1참가 물질
3
실험 절차
In a similar manner 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(3-methylbenzyl)-4-pyrimidone dihydrochloride m.p. 203.5°-205° (ex ethanol) may be prepared from 5-(3-methylbenzyl)-2-thiouracil.
출처 및 근거
- ORD 기록
- ord-2d33e5c7285146a1a0b63e61f080f043
- 출처 데이터셋
- uspto-grants-1979_06
- 특허 번호
- US04159329
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