HCID 46947722, 화합물 → HCID 87134732, 화합물

HRID 2370609노트

반응식

HRID 2370609 반응식
[CH3:1][C:2]1([CH3:46])[C:6](=[O:7])[N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:20])[CH2:16][N:17]([CH3:19])[CH3:18])=[C:10]([C:21]([F:24])([F:23])[F:22])[CH:9]=2)[C:4](=[O:25])[N:3]1[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][S:35][CH2:36][CH2:37][CH2:38][C:39]([F:45])([F:44])[C:40]([F:43])([F:42])[F:41].CC1(C)N(CCCCCCCCCSCCCC(F)(F)C(F)(F)F)C(=[O:73])N(C2C=CC([N+]([O-])=O)=C(C(F)(F)F)C=2)C1=O>>[CH3:1][C:2]1([CH3:46])[C:6](=[O:7])[N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:20])[CH2:16][N:17]([CH3:18])[CH3:19])=[C:10]([C:21]([F:24])([F:23])[F:22])[CH:9]=2)[C:4](=[O:25])[N:3]1[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][S:35]([CH2:36][CH2:37][CH2:38][C:39]([F:45])([F:44])[C:40]([F:41])([F:42])[F:43])=[O:73]

참가 물질

3

반응물 2

HCID 46947722HCID 46947722, 화합물HCID 87134921HCID 87134921, 화합물

생성물 1

HCID 87134732HCID 87134732, 화합물수율 65%

실험 절차

Compound 43a described below was synthesized according to a method similar to that described in Example 2 using the compound of Example 42 as starting reagent replacing the compound of Example 1. The expected compound is obtained in the form of a pale yellow oil with a yield of 65%.

후처리

  1. custombelow was synthesized

출처 및 근거

ORD 기록
ord-a58d8bdcba55496c81cfd28291ed00f1
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08710091B2

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