Acetic Acid → 1,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-methoxyphenyl)-

HRID 237086노트

반응식

HRID 237086 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([CH:11]=O)=O)=[CH:5][CH:4]=1.[NH2:13][C:14]1[N:18]([NH2:19])[CH:17]=[N:16][N:15]=1.C([O-])(=O)C.[Na+].C(O)(=O)C>O>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:11]=[N:19][N:18]3[CH:17]=[N:16][N:15]=[C:14]3[N:13]=2)=[CH:5][CH:4]=1

참가 물질

6

반응물 4

HCID 176Acetic AcidHCID 70643(4-Methoxyphenyl)glyoxalHCID 517045Sodium AcetateHCID 5671443,4-Diamino-1,2,4-triazole

생성물 1

HCID 30545031,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-methoxyphenyl)-

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A solution of 9.1 g. of p-methoxyphenylglyoxal, 6.7 g. of 3,4-diamino-4H-1,2,4-triazole and 4.1 g. of sodium acetate in 90 ml. of 67% acetic acid is heated on a steam bath for 1/2 hour. Water is added and heating is continued until crystals separate. The mixture is cooled and filtered. The precipitate is washed with water, ethanol and then hexane giving the desired product as yellow plates, m.p. 282.5°-284.5° C.

후처리

  1. temperatureheating
  2. customseparate
  3. temperatureThe mixture is cooled
  4. filtrationfiltered
  5. washThe precipitate is washed with water, ethanol

출처 및 근거

ORD 기록
ord-3ee8d8310eaf43c7b4bc3e932185a9a1
출처 데이터셋
uspto-grants-1979_06
특허 번호
US04159375

반응 노트

불러오는 중…