Methanol → 3-Hydrazino-5-(alpha,alpha,alpha-trifluoro-m-tolyl)-1,2,4-triazine

HRID 237094노트

반응식

HRID 237094 반응식
CS[C:3]1[N:4]=[N:5][CH:6]=[C:7]([C:9]2[CH:10]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:13][CH:14]=2)[N:8]=1.CO.[NH2:21][NH2:22]>O1CCCC1>[NH:21]([C:3]1[N:4]=[N:5][CH:6]=[C:7]([C:9]2[CH:10]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:13][CH:14]=2)[N:8]=1)[NH2:22]

참가 물질

5

반응물 3

HCID 887MethanolHCID 9321HydrazineHCID 3053026as-Triazine, 3-(methylthio)-5-(alpha,alpha,alpha-trifluoro-m-tolyl)-

생성물 1

HCID 30530543-Hydrazino-5-(alpha,alpha,alpha-trifluoro-m-tolyl)-1,2,4-triazine

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

To a solution of 22.8 g. of 3-methylthio-5-(α,α,α-trifluoro-m-tolyl)-1,2,4-triazine in a mixture of 30 ml. of methanol and 35 ml. of tetrahydrofuran is added 4.84 ml. of 95% hydrazine. The mixture is refluxed for 48 hours, cooled and the solid is collected by filtration giving 3-hydrazino-5-(α,α,α-trifluoro-m-tolyl)-1,2,4-triazine as yellow needles.

후처리

  1. temperatureThe mixture is refluxed for 48 hours
  2. temperaturecooled
  3. filtrationthe solid is collected by filtration

출처 및 근거

ORD 기록
ord-7ed030818d0e4b6199eecbd3e47c4e91
출처 데이터셋
uspto-grants-1979_06
특허 번호
US04159375

반응 노트

불러오는 중…