1,3-Cyclohexanedione → 2-Bromocyclohexane-1,3-dione

HRID 2371046노트

반응식

HRID 2371046 반응식
[C:1]1(=[O:8])[CH2:6][CH2:5][CH2:4][C:3](=[O:7])[CH2:2]1.[Br:9]Br>>[Br:9][CH:2]1[C:3](=[O:7])[CH2:4][CH2:5][CH2:6][C:1]1=[O:8]

참가 물질

3

반응물 2

HCID 104341,3-CyclohexanedioneHCID 24408Bromine

생성물 1

HCID 27704762-Bromocyclohexane-1,3-dione

실험 절차

Cyclohexane-1,3-dione (11.2 g, 0.1 mol) was suspended in ice water (70 mL) and bromine (5.16 mL, 0.1 mol) was added dropwise over 5 minutes. The resulting suspension was stirred at room temperature for 3 hours. The suspension was filtered and the solid was stirred in water (200 mL) for 30 minutes. The solid was collected by vacuum filtration, rinsed with water, and dried to render crude product. The crude product was recrystallized from ethanol to produce the title compound.

후처리

  1. filtrationThe suspension was filtered
  2. stirringthe solid was stirred in water (200 mL) for 30 minutes
  3. filtrationThe solid was collected by vacuum filtration
  4. washrinsed with water
  5. customdried
  6. customThe crude product was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-5964cbc9c2f84a74be3317488fc17b92
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08710245B2

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