Hydrazine → HCID 67905363, 화합물

HRID 2371421노트

반응식

HRID 2371421 반응식
[NH2:1][NH2:2].[O:3]=[C:4]1[CH:9]([CH2:10][C:11](OC)=[O:12])[S:8](=[O:16])(=[O:15])[C:7]2[S:17][C:18]([S:20](=[O:23])(=[O:22])[NH2:21])=[CH:19][C:6]=2[NH:5]1>CO>[S:20]([C:18]1[S:17][C:7]2[S:8](=[O:16])(=[O:15])[CH:9]([CH2:10][C:11]([NH:1][NH2:2])=[O:12])[C:4](=[O:3])[NH:5][C:6]=2[CH:19]=1)(=[O:23])(=[O:22])[NH2:21]

참가 물질

4

반응물 2

HCID 9321HydrazineHCID 86745510HCID 86745510, 화합물

생성물 1

HCID 67905363HCID 67905363, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Anhydrous hydrazine (1 ml) was added to a solution of methyl (2,3-dihydro-2,4,4-trioxo-6-sulfamoyl-1H-thieno[2,3-b][1,4]thiazin-3-yl)acetate (1.0 g) in methanol (10 ml) at ambient temperature with stirring. After 5-6 hours, the methanol was removed under reduced pressure and the residue was treated with water (10 ml). The pH was adjusted to 6.5 and the resulting precipitate was collected, rinsed with water and dried under vacuum to give 0.40 g (2,3-dihydro-6-sulfamoyl-2,4,4-trioxo-1H-thieno[2,3-b][1,4]thiazin-3-yl)acetic acid hydrazide, mp 230° C., dec.

후처리

  1. customthe methanol was removed under reduced pressure
  2. additionthe residue was treated with water (10 ml)
  3. customthe resulting precipitate was collected
  4. washrinsed with water
  5. customdried under vacuum

출처 및 근거

ORD 기록
ord-17f5911b7ee34a7c88cb981e686592f3
출처 데이터셋
uspto-grants-1992_03
특허 번호
US05093332

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