Thionyl Chloride → HCID 556978, 화합물

HRID 2371434노트

반응식

HRID 2371434 반응식
[CH:1]1([CH3:15])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([O:10][CH2:11][C:12](O)=[O:13])[CH2:2]1.S(Cl)([Cl:18])=O>>[CH:1]1([CH3:15])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([O:10][CH2:11][C:12]([Cl:18])=[O:13])[CH2:2]1

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 978142-((5-Methyl-2-(1-methylethyl)cyclohexyl)oxy)acetic acid

생성물 1

HCID 556978HCID 556978, 화합물수율 107.4%

실험 절차

0.771 g (3.6 mmol) of (-)-menthoxyacetic acid is stirred under reflux with 2.1 g of thionyl chloride for 4 to 5 h. The thionyl chloride is first removed from the solution by distillation under reduced pressure. 3 ml of dry benzene are then added in order to remove residual thionyl chloride by means of vacuum distillation. 0.9 g of the title compound is obtained.

후처리

  1. customThe thionyl chloride is first removed from the solution by distillation under reduced pressure
  2. addition3 ml of dry benzene are then added in order
  3. customto remove residual thionyl chloride
  4. distillationby means of vacuum distillation

출처 및 근거

ORD 기록
ord-e451021af54e4d49b89adeba7e1e916b
출처 데이터셋
uspto-grants-1992_03
특허 번호
US05093350

반응 노트

불러오는 중…