diethyl 3,4-dihydro-7-[3-(4-chlorophenoxy)propoxy]-4-oxo-8-propyl-2H-1-benzopyran-2,2-dipropanoate → 3,4-dihydro-7-[3-(2-naphthalenyloxy)propoxy]-4-oxo-8-propyl-2H-1-benzopyran-2,2-dipropanoic acid
반응식
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:40]=[CH:39][C:19]2[C:20](=[O:38])[CH2:21][C:22]([CH2:31][CH2:32][C:33]([O:35]CC)=[O:34])([CH2:24][CH2:25][C:26]([O:28]CC)=[O:27])[O:23][C:18]=2[C:17]=1[CH2:41][CH2:42][CH3:43].ClC1C=CC(OCCCOC2C=CC3C(=O)CC(CCC(OCC)=O)(CCC(OCC)=O)OC=3C=2CCC)=CC=1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:40]=[CH:39][C:19]2[C:20](=[O:38])[CH2:21][C:22]([CH2:31][CH2:32][C:33]([OH:35])=[O:34])([CH2:24][CH2:25][C:26]([OH:28])=[O:27])[O:23][C:18]=2[C:17]=1[CH2:41][CH2:42][CH3:43]참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared by the method of Example 22 substituting 539 mg of the title product of Example 23 for the title product of Example 21. Crystallization from 5:1 ethyl acetate:hexane yielded 303 mg, m.p. 157.5°-158° C.