Dimethylamine → HCID 57271419, 화합물

HRID 2372382노트

반응식

HRID 2372382 반응식
[CH:1]([O:4][C:5]([C:7]1[CH:8]([CH3:28])[CH2:9][N:10]2[C:14](=[CH:15][C:16]([O:18]C3C=CC([N+]([O-])=O)=CC=3)=O)[CH2:13][S:12][C:11]=12)=[O:6])([CH3:3])[CH3:2].[CH3:29][NH:30][CH3:31]>O>[CH3:29][N:30]([CH3:31])[C:16](=[O:18])[CH:15]=[C:14]1[CH2:13][S:12][C:11]2=[C:7]([C:5]([O:4][CH:1]([CH3:2])[CH3:3])=[O:6])[CH:8]([CH3:28])[CH2:9][N:10]12

참가 물질

4

반응물 2

HCID 674DimethylamineHCID 867455674-Nitrophenyl (7-Isopropoxycarbonyl-6-methyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)acetate

생성물 1

HCID 57271419HCID 57271419, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To 1.50 g of 4-nitrophenyl (7-isopropoxycarbonyl-6-methyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)acetate, was added 40 ml of a 25% aqueous solution of dimethylamine and the mixture was stirred at room temperature for 3 days. 40 ml of water was added thereto and the precipitate thus formed was collected by filtration, washed with water and dissolved in chloroform. After drying and distilling off the solvent, the crude crystals thus obtained were recrystallized from a solvent mixture of ether and n-hexane. Thus 0.6 g of the title compound was obtained.

후처리

  1. customthe precipitate thus formed
  2. filtrationwas collected by filtration
  3. washwashed with water
  4. dissolutiondissolved in chloroform
  5. customAfter drying
  6. distillationdistilling off the solvent
  7. customthe crude crystals thus obtained
  8. customwere recrystallized from a solvent mixture of ether and n-hexane

출처 및 근거

ORD 기록
ord-62dd0dd976584d1f8d41b8de28be302a
출처 데이터셋
uspto-grants-1992_03
특허 번호
US05098919

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