Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethylenediamine → p-Hydroxymethylbenzoylaminoethylamine acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethylenediamine | HCID 3301 | — |
| 반응물 | Ethyl 4-(hydroxymethyl)benzoate | HCID 12480307 | — |
| 생성물 | p-Hydroxymethylbenzoylaminoethylamine acetate | HCID 67918850 | 49% |
반응 단계
Ethyl p- hydroxymethylbenzoate (0.51 g, 2.8 mmol) was dissolved in ethylene diamine and heated on a steam bath overnight. The volume was reduced under a stream of nitrogen and the residue was chromatographed by preparative thin layer chromatography (silica, CHCl3 : MeOH:HOAc, 10:10:1) to yield the product as an oil (0.35 g, 49% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05098996 |
| 출처 데이터셋 | uspto-grants-1992_03 |
| ORD ID | ord-a191819783a74eb5b51fd002fccb8f73 |
| 출처 메모 | uspto-grants-1992_03 |