Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-Xylene → N-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propanamido]-4-methylhexahydrophthalimide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-Xylene | HCID 7237 | — |
| 반응물 | 3,5-Di-tert-butyl-4-hydroxyhydrocinnamic acid hydrazide | HCID 64865 | — |
| 반응물 | Hexahydro-4-methylphthalic anhydride | HCID 86876 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propanamido]-4-methylhexahydrophthalimide | HCID 19902401 | 100.5% |
반응 단계
A mixture of 4-methylhexahydrophthalic anhydride (32.8 g, 200 mmol), 3-(3,5-di-t-butyl-4-hydroxyphenyl)propanoic acid hydrazide (58.4 g, 220 mmol) and 650 ml of xylene was refluxed for 90 minutes under a nitrogen atmosphere with the azeotropic removal of water. The solvent was removed on a rotary evaporator to afford approximately 89 g of a white solid having a melting range of 87°-92° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05100940 |
| 출처 데이터셋 | uspto-grants-1992_03 |
| ORD ID | ord-88fbdd1f3b4749738a1e86582e79995e |
| 출처 메모 | uspto-grants-1992_03 |