Acetic Acid → HCID 19790384, 화합물

HRID 2372924노트

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HRID 2372924 반응식
S(Cl)([Cl:4])(=O)=O.[Cl:6][C:7]1[NH:8][C:9]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[C:16]([Cl:21])[CH:15]=2)=[CH:10][C:11]=1[C:12]#[N:13].CCOCC.C(O)(=O)C>CCCCCC>[Cl:6][C:7]1[NH:8][C:9]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[C:16]([Cl:21])[CH:15]=2)=[C:10]([Cl:4])[C:11]=1[C:12]#[N:13]

참가 물질

6

반응물 4

HCID 176Acetic AcidHCID 3283Diethyl EtherHCID 24648Sulfuryl chlorideHCID 11022008HCID 11022008, 화합물

생성물 1

HCID 19790384HCID 19790384, 화합물

시약·촉매·용매 1

HCID 8058Hexane용매

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온도
0 °C

실험 절차

Sulfuryl chloride (1.8 g) is added dropwise to a 0° C. mixture of 2-chloro-5-(3,4-dichlorophenyl)pyrrole-3-carbonitrile, ether (30 mL) and acetic acid (30 mL). After stirring for 2 hours at 0° C., the reaction mixture is poured into an ice-water slurry. The cold mixture is diluted with hexane and the solids are collected and dried to give the title compound as a beige solid (mp >200° C.) which is identified by 13C NMR spectral analysis.

후처리

  1. customthe solids are collected
  2. customdried

출처 및 근거

ORD 기록
ord-13e678072cb8448f85f006928eb97e14
출처 데이터셋
uspto-grants-1992_03
특허 번호
US05101042

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