Water → (E)-1,4-Bis(-4-bromostyryl)benzene

참여 물질

역할	이름	HCID	투입량
반응물	Water	HCID 962	—
반응물	Sodium Hydroxide	HCID 14798	—
반응물	4-Bromobenzaldehyde	HCID 70741	—
반응물	Phosphonic acid, P,P'-(1,4-phenylenebis(methylene))bis-, P,P,P',P'-tetraethyl ester	HCID 78303	—
촉매	Tetrabutylammonium Iodide	HCID 67553	—
용매	Benzene	HCID 241	—
생성물	(E)-1,4-Bis(-4-bromostyryl)benzene	HCID 12266563	—

반응 단계

50% aqueous sodium hydroxide (20 ml) was added to a solution of tetraethyl p-xylylenebisphosphonate (2.40 g, 6.35 mmol) (25) and 4-bromobenzaldehyde (2.41 g, 13.02 mmol) in 10 ml of benzene. Tetra-n-butylammonium iodide (148 mmg) was added and the mixture was refluxed under nitrogen for 1 hour. The reaction mixture was allowed to cool and diluted by the addition of water (25 ml). A yellow solid was collected and washed three times with water, methanol and ether. The product was purified by recrystallization from xylenes and was isolated in 61.9% (1.73 g) yield (Product is insoluble in standard solvents).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07459106B2
출처 데이터셋	uspto-grants-2008_12
ORD ID	ord-c9179945d71441d98244d7e77c38dd4d
출처 메모	uspto-grants-2008_12