Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 4-Chloro-7-nitroquinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 7-Nitroquinazolin-4(3H)-one | HCID 86222800 | — |
| 생성물 | 4-Chloro-7-nitroquinazoline | HCID 830680 | — |
반응 단계
To a solution of 7-nitroquinazolin-4(3H)-one (2.0 g, 10.5 mmol) in 40 ml thionyl chloride was added 0.8 ml of DMF and the mixture was heated at reflux overnight then evaporated to dryness to provide crude 4-chloro-7-nitroquinazoline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08642582B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-f0f7d6401cd4487e98e4fe40bbd46dba |
| 출처 메모 | uspto-grants-2014_02 |