Aniline → HCID 10410312, 화합물

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[C:1]([C:4]1[C:9]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=2)=[N:8][N:7]([CH2:19][CH3:20])[C:6](=[O:21])[C:5]=1[N+:22]([O-])=O)(=[O:3])[CH3:2].N[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[C:1]([C:4]1[C:9]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=2)=[N:8][N:7]([CH2:19][CH3:20])[C:6](=[O:21])[C:5]=1[NH:22][C:30]1[C:31]2[C:26](=[CH:2][CH:1]=[CH:4][CH:5]=2)[CH:27]=[CH:28][CH:29]=1)(=[O:3])[CH3:2]

참가 물질

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HCID 6115Aniline

HCID 10544525HCID 10544525, 화합물

생성물 1

HCID 10410312HCID 10410312, 화합물

실험 절차

The title compounds were synthesized from 5-acetyl-2-ethyl-4-nitro-6-(3-nitrophenyl)pyridazin-3(2H)-one (Dal Piaz, V et al, J. Med. Chem. 1997, 40, 1417) and the corresponding aniline following the procedure of Example 49. The ESI/MS data and HPLC retention times are summarized in Table 10.

출처 및 근거

ORD 기록: ord-f3b9e3f3daa945948172d7c1f7f630b3
출처 데이터셋: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07459453B2

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