2-Methoxyethyl chloroformate → HCID 178462934, 화합물

HRID 2374555노트

반응식

HRID 2374555 반응식
[NH2:1][C:2]1[C:3]([C:7]2[NH:23][C:10]3=[CH:11][C:12]4[C:13]([CH3:22])([CH3:21])[C:14](=[O:20])[N:15]([CH2:18][CH3:19])[C:16]=4[CH:17]=[C:9]3[N:8]=2)=[N:4][NH:5][CH:6]=1.Cl[C:25]([O:27][CH2:28][CH2:29][O:30][CH3:31])=[O:26]>>[CH3:31][O:30][CH2:29][CH2:28][O:27][C:25](=[O:26])[NH:1][C:2]1[C:3]([C:7]2[NH:23][C:10]3=[CH:11][C:12]4[C:13]([CH3:22])([CH3:21])[C:14](=[O:20])[N:15]([CH2:18][CH3:19])[C:16]=4[CH:17]=[C:9]3[N:8]=2)=[N:4][NH:5][CH:6]=1

참가 물질

3

반응물 2

HCID 694002-Methoxyethyl chloroformateHCID 178462936HCID 178462936, 화합물

생성물 1

HCID 178462934HCID 178462934, 화합물

실험 절차

[3-(5-Ethyl-7,7-dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-1H-pyrazol-4-yl]-carbamic acid 2-methoxy-ethyl ester was prepared using 2-(4-amino-1H-pyrazol-3-yl)-5-ethyl-7,7-dimethyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one (250 mg, 0.81 mmol) and 2-methoxyethyl chloroformate (103 μl, 0.89 mmol). The title compound was obtained as yellow powder (196 mg, 59%).

후처리

  1. custom[3-(5-Ethyl-7,7-dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-1H-pyrazol-4-yl]-carbamic acid 2-methoxy-ethyl ester was prepared

출처 및 근거

ORD 기록
ord-b88c438b6f6e49768ca56ec550d55074
출처 데이터셋
uspto-grants-2008_12
특허 번호
US07462639B2

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