Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Dimethoxyaniline → N-[3,4-bis(methyloxy)phenyl]-5-methyl-7-phenylimidazo[5,1-f][1,2,4]triazin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Dimethoxyaniline | HCID 22770 | — |
| 반응물 | 5-Methyl-2-(methylthio)-7-phenylimidazo[5,1-F][1,2,4]triazine | HCID 53471832 | — |
| 반응물 | 5-Methyl-2-(methylsulfonyl)-7-phenylimidazo[5,1-F][1,2,4]triazine | HCID 53471833 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-[3,4-bis(methyloxy)phenyl]-5-methyl-7-phenylimidazo[5,1-f][1,2,4]triazin-2-amine | HCID 11405758 | 36.6% |
반응 단계
Applying the displacement procedure, using 5-methyl-2-(methylthio)-7-phenylimidazo[5,1-f][1,2,4]triazine (Intermediate 72) (50 mg, 0.17 mmol), 3,4-dimethoxyaniline (26.5 mg, 0.17 mmol) and ethanol (2.5 mL) to afford N-[3,4-bis(methyloxy)phenyl]-5-methyl-7-phenylimidazo[5,1-f][1,2,4]triazin-2-amine (22.5 mg) as a yellow solid. MS m/z 362 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07462614B2 |
| 출처 데이터셋 | uspto-grants-2008_12 |
| ORD ID | ord-e5c039399f834a8f8316774027d03abc |
| 출처 메모 | uspto-grants-2008_12 |