Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-Nitrophenyl)oxazole → 4-(Oxazol-4-yl)aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-Nitrophenyl)oxazole | HCID 14567797 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Tetrahydrofuran ethanol | HCID 21873804 | — |
| 생성물 | 4-(Oxazol-4-yl)aniline | HCID 22397853 | — |
반응 단계
5% Palladium-carbon powder was added to an ethanol-tetrahydrofuran mixed suspension of 4-(4-nitrophenyl)-1,3-oxazol and stirred for 12 hours at room temperature in a hydrogen atmosphere. The reaction solution was filtered through Celite and the filtrate was evaporated under reduced pressure. The resulting crude product is purified with a silica gel column chromatography to obtain [4-(1,3-oxazol-4-yl)phenyl]amine (pale yellow solid). Electron Impact-MS(M)+: 160.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07465748B2 |
| 출처 데이터셋 | uspto-grants-2008_12 |
| ORD ID | ord-1519ff411b454708a102c24fe406bc08 |
| 출처 메모 | uspto-grants-2008_12 |