참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrogen Peroxide | HCID 784 | — |
| 반응물 | 5-Ethyl-2-pyridineethanol | HCID 78894 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-(5-Ethyl-1-oxidopyridin-1-ium-2-yl)ethanol | HCID 66823399 | 81.8% |
반응 단계
To a solution of 100 g (0.655 mol) 2-(5-ethyl-pyridin-2-yl)-ethanol in 500 mL acetic acid was added 118 g (1.049 mol) 30% hydrogen peroxide at 25-30° C. Reaction mixture was refluxed at 100° C. (tlc) for 14 hr. After completion of the reaction acetic acid was removed under vacuum, and the residual mass was poured in excess water and made alkaline by 10% Na2CO3 solution. Product was extracted with ethyl acetate and after concentrating ethyl acetate in vacuo, 89.58 g (81%) crystalline product was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07465801B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_12 |
|---|
| ORD ID | ord-dc117a4c3aeb4998b37400df6a240b5d |
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| 출처 메모 | uspto-grants-2008_12 |
|---|
