2-Bromo-4-fluoro-1-(methoxymethoxymethyl)benzene → HCID 11299354, 화합물

반응식

[C:1]([C:3]1[CH:4]=[C:5]([B:9]2[O:13][CH2:12][CH2:11]O2)[CH:6]=[CH:7][CH:8]=1)#[N:2].Br[C:15]1[CH:20]=[C:19]([F:21])[CH:18]=[CH:17]C=1COCOC>>[F:21][C:19]1[CH:18]=[CH:17][C:11]2[CH2:12][O:13][B:9]([C:5]3[CH:4]=[C:3]([CH:8]=[CH:7][CH:6]=3)[C:1]#[N:2])[C:15]=2[CH:20]=1

참가 물질

반응물 2

HCID 667046952-Bromo-4-fluoro-1-(methoxymethoxymethyl)benzene

HCID 667383483-(1,3,2-Dioxaborolan-2-yl)benzonitrile

생성물 1

HCID 11299354HCID 11299354, 화합물

실험 절차

This was prepared as per the procedure in Example 11, from 2-(3-cyanophenyl)-[1,3,2]-dioxaborolane and 1-bromo-5-fluoro-2-((methoxymethoxy)methyl)benzene to afford white crystalline product.

후처리

customto afford white crystalline product

출처 및 근거

ORD 기록: ord-e02703cdea224375bbb6713344483143
출처 데이터셋: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07465836B2

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