Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromobenzenesulfonyl chloride → N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-bromobenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromobenzenesulfonyl chloride | HCID 520403 | — |
| 반응물 | 3-Methoxy-5-methyl-2-pyrazinamine | HCID 10701894 | — |
| 생성물 | N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-bromobenzenesulfonamide | HCID 22574647 | — |
반응 단계
2-amino-3-methoxy-5-methylpyrazine (1.50 g, 10.8 mmol; synthesized according to Bradbury, R. H., et. al. J. Med. Chem. 1997, 40, 996-1004) and 2-bromobenzenesulfonyl chloride (2.80 g, 11.0 mmol) were reacted according to the procedure of Example 25, Step A. 44A was a pink solid, 2.0 g (52%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06852745B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-32684a7f2dc54df6a229f66d61bb8a06 |
| 출처 메모 | uspto-grants-2005_02 |