2-Bromo-5-iodo-1,3-dimethylbenzene → 4-(4-Bromo-3,5-dimethyl-phenyl)-2-methoxy-pyridine

HRID 237636노트

반응식

HRID 237636 반응식
[CH3:1][O:2][C:3]1[CH:8]=[C:7](B(O)O)[CH:6]=[CH:5][N:4]=1.[Br:12][C:13]1[C:18]([CH3:19])=[CH:17][C:16](I)=[CH:15][C:14]=1[CH3:21]>>[Br:12][C:13]1[C:18]([CH3:19])=[CH:17][C:16]([C:7]2[CH:6]=[CH:5][N:4]=[C:3]([O:2][CH3:1])[CH:8]=2)=[CH:15][C:14]=1[CH3:21]

참가 물질

3

반응물 2

HCID 207480372-Bromo-5-iodo-1,3-dimethylbenzeneHCID 23546919(2-Methoxypyridin-4-yl)boronic acid

생성물 1

HCID 866973094-(4-Bromo-3,5-dimethyl-phenyl)-2-methoxy-pyridine

실험 절차

The title compound is prepared from 2-methoxy-pyridine-4-boronic acid and 2-bromo-5-iodo-1,3-dimethyl-benzene following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 9): tR=1.24 min; Mass spectrum (ESI+): m/z=293/295 (Br) [M+H]+.

출처 및 근거

ORD 기록
ord-690d248bcb1747b593004cfe50051fd6
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08642585B2

반응 노트

불러오는 중…