Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isobutylamine → 4-Isobutyl-3-nitro quinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isobutylamine | HCID 6558 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 4-Chloro-3-nitroquinoline | HCID 11275808 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 4-Isobutyl-3-nitro quinoline | HCID 22590498 | — |
반응 단계
4-chloro-3-nitro-quinoline is reacted with isobutyl amine in the presence of triethylamine (TEA) at between −10 and +15° C. in toluene, while excluding moisture. After washing and phase separation, the organic solution is ready for the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06852861B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-36905fa681b1473c9ca583a21c17dc15 |
| 출처 메모 | uspto-grants-2005_02 |